COPD, Inspiratory Muscle Weakness
Conditions
Brief summary
The additional effect of inspiratory muscle training as an adjunct to a general exercise training program in patients with COPD with inspiratory muscle weakness will be studied. The main hypothesis is that inspiratory muscle training combined with an exercise training program improves functional exercise capacity more than an exercise training program without the addition of an inspiratory muscle training program.
Interventions
OTHERInspiratory Muscle Training
Sponsors
KU Leuven
Schön Klinik Berchtesgadener Land
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
40 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Patients with COPD * Eligible to participate in an inpatient pulmonary rehabilitation program of 3 weeks * Pi,max \<60 centimeters of water or \<50% of the predicted normal value
Exclusion criteria
* Major comorbidities preventing successful participation in an 8 week exercise training intervention * use of non-invasive ventilation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 6-Minute walking distance | change from the beginning at 3 weeks of a inpatient pulmonary rehabilitation program |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| exercise capacity (constant work rate test) | change from the beginning at 3 weeks of a inpatient pulmonary rehabilitation program | — |
| maximal inspiratory pressure (PImax) | change from the beginning at 3 weeks of a inpatient pulmonary rehabilitation program | — |
| inspiratory muscle endurance capacity | change from the beginning at 3 weeks of a inpatient pulmonary rehabilitation program | — |
| dyspnea | change from the beginning at 3 weeks of a inpatient pulmonary rehabilitation program | measured via Borg-scale at rest, during 6-minute walking distance, during constant work rate test at iso-time, during inspiratory muscle endurance capacity test |
Countries
Germany
Outcome results
None listed