Stroke
Conditions
Brief summary
The purpose of this study is to determine whether a culturally-sensitive multipronged post-discharge intervention can significantly reduce blood pressure, enhance achievement of guideline recommended targets for risk factor control, and lower recurrent vascular events in a low-income and middle-income (LMIC). The study will have 2 Phases - a qualitative phase (Phase 1) lasting less than one year involving development of the intervention through focus group methodologies and structured interviews, and a clinical trial phase (Phase 2)lasting 3 years involving a randomized trial testing the efficacy of the intervention.
Detailed description
This research seeks to develop an effective and sustainable way of reducing the devastating and deadly impact of stroke in a low-income region of the world with poor medical infrastructure. It will do so by focusing on improving the treatment of the condition most closely tied to stroke, hypertension, using novel methods that incorporate the input of the local community. If successful, the strategy could serve as a ready model to be adapted by decision-makers in other under-resourced areas for lessening the burden of stroke(and other major public health challenges).
Interventions
BEHAVIORALTHRIVES
Pre-appointment phone text In-clinic educational video Patient report card Post-clinic phone text Outpatient stroke registry
Sponsors
Medical University of South Carolina
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Phase 1: Inclusion Criteria: Age ≥ 18 years Stroke within one year access to mobile phone.
Exclusion criteria
Any medical condition that would limit participation in follow up assessments, Severe cognitive impairment/dementia (MMSE ≤24) Severe global disability (modified Rankin Score ≥ 3).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Reduction in systolic blood pressure | 1 year | Reduction in systolic blood pressure at one year post-discharge in stroke patients. |
Secondary
| Measure | Time frame |
|---|---|
| Reduced rate of subsequent primary vascular event | 1 year |
Other
| Measure | Time frame |
|---|---|
| Reduction of disability and enhanced quality of life. | 1 year |
Countries
Nigeria
Outcome results
None listed