Acute High-risk Abdominal Surgery Study - an Optimized Perioperative Course

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01899885

Acronym

AHA

Enrollment

1200

Registered

2013-07-16

Start date

2013-06-30

Completion date

2015-06-30

Last updated

2015-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intestinal Obstruction, Perforated Viscus

Keywords

Emergency laparotomy, Emergency laparoscopy

Brief summary

The objective of this study is to implement an optimized perioperative course for patients undergoing acute high-risk abdominal surgery in order to improve the outcome. The optimized perioperative course consists of a number of interventions carried out before, during and after surgery.

Detailed description

Emergency surgery is associated with high mortality rates, post-operative complications and prolonged duration of hospital admission. The investigators will implement a multidisciplinary optimized perioperative course consisting of a number of interventions carried out before, during and after surgery. Hypothesis: An optimized perioperative course will reduce the 30-day mortality in emergency abdominal surgery patients. The investigators will do a post-hoc analysis of the data registered.

Interventions

PROCEDUREAHA (Acute Highrisk Abdominalsurgery): Optimized Course

optimized course: Intervention before, during and after abdominal surgery. Focus on fast track with multimodal standardized intervention: 1. standardized preparing for surgery including high dose antibiotics and epidural analgesia etc. and transfer to intermediate care before surgery (the post-anaesthesia care unit) 2. GDT-LiDCO fluid management pre-, per- and postoperative 3. Postoperative triage to 24 hour intermediate care based on ASA score and Surgical Apgar Score 4. Focus on early mobilization, fysiotherapy and optimal nutrition postoperatively

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* patients undergoing primary emergency laparotomy or laparoscopy * patients undergoing reoperation after abdominal surgery. * Age \> 18 years

Exclusion criteria

* Appendectomy * Emergency laparoscopic cholecystectomy * Emergency diagnostic laparoscopy without intervention

Design outcomes

Primary

Measure	Time frame
mortality rate	Within 30 days of surgery

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 27, 2026