Skip to content

Prophylactic Antibiotic Treatment for Hand Lacerations Involving Flexor and/or Extensor Tendon

Prophylactic Antibiotic Treatment for Hand Lacerations Involving Flexor and/or Extensor Tendon

Status
Completed
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01899781
Enrollment
24
Registered
2013-07-15
Start date
2013-08-31
Completion date
2015-11-30
Last updated
2020-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Clean Laceration, Hand Laceration, No Bone Involved, Tendon Involved

Keywords

Lacerations, Tendons, Antobiotic

Brief summary

The investigators assume that simple hand lacerations involving flexors or extensors tendons, do not require prophylactic antibiotic treatment to prevent wound infection.

Detailed description

Hand lacerations are divided to complicated which involves tendons, nerves, bones, and joints, and simple which involves only cutaneous and subcutaneous tissue. prophylactic antibiotic should not be given in a clean simple lacerations, and should be given when a bone is involve (open fracture). But there is not enough data, weather prophylactic antibiotic treatment should be given when only tendons are involved. The investigators will examine 2 groups of 30 patients each with clean hand lacerations involving tendons. One group will be treated with prophylactic antibiotic and the other wont be treated, randomly. The investigators assume that the rate of wound infection wont be different between the 2 groups.

Interventions

DRUGAntibiotic-Cefamezin

Sponsors

HaEmek Medical Center, Israel
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
13 Years to 75 Years
Healthy volunteers
Yes

Inclusion criteria

* Hand laceration * Tendon involeved * Clean laceration * No bone involved

Exclusion criteria

* Pregnant * Children * Immunocompremised patients * Dirty lacerations

Design outcomes

Primary

MeasureTime frameDescription
rate of wound infections2 yearssigns of wound/tissue infection, levels of WBC, ESR, CRP

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026