Hypercapnia, Hypoxia and Hypercapnia, Pulmonary Vascular Sensibility in Hypoxia
Conditions
Brief summary
The aim of this study is to describe the pulmonary hemodynamic evolution at rest and during a short constant load exercise in 4 conditions : * normoxia * hypoxia * hypercapnia * association hypoxia and hypercapnia
Interventions
DEVICEHypercapnia inhalation (Altitrainer NP 190)
Hypercapnia inhalation using an Altitrainer NP 190
DEVICEHypoxia and hypercapnia (Altitrainer NP 190)
Hypoxia and hypercapnia inhalation using an Altitrainer NP 190
DEVICEHypoxia inhalation (Altitrainer NP 190)
Hypoxia inhalation using an Altitrainer NP 190
Sponsors
University Hospital, Strasbourg, France
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
MALE
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* healthy male * exercise capacity between 100 and 130 % of theorical values
Exclusion criteria
* smoker * headache * impossibility to perform an exercise test * no tricuspid regurgitation on the echocardiography
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Systolic Artery Pulmonary Pressure(sPAP) (echocardiography, Cardiac output (impedancemetry), Cardiorespiratory parameters | at the end of the 30th minutes constant load exercise | At rest and during exercise for each condition |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Dyspnea and muscle leg discomfort using a Borg Scale | at the end of the 30th minutes constant load exercise | In each conditions at rest and during exercise |
Countries
France
Outcome results
None listed