Amyotrophic Lateral Sclerosis
Conditions
Brief summary
ALS is a severe progressive neurodegenerative disease characterized by degeneration motor neurons leading to death in 3 to 5 years. Gradually in time, the patient deprived of all motor skills as well as the possibility of communication written and oral developing a state close Locked In Syndrome (LIS). The main objective is to establish the feasibility of brain-computer interface using the pathological condition, with dependent disabled subjects as a means of communication.
Interventions
DEVICEcommunication system P300 Speller
Sponsors
Centre Hospitalier Universitaire de Nice
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* age \>= 18 * have a diagnosis of ALS suspected, possible, probable with EMG * be able to follow the study process and to comply with the schedule of visits upon entry into the study * understand the purpose of the study * expressing P300 wave in the conditions of the study
Exclusion criteria
* have a mental illness or clinical dementia defined clinically significant may hinder the patient's ability to follow the procedures of the study * have a significant history of photosensitive epilepsy * have a history of allergy to the gel used for the electrodes * Major protected by law (guardianship, curators) * have uncorrectable visual disorders * not being able to maintain a sitting position and focus on a computer screen for more than 30 min.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the full achievement of copy spelling and free spelling tests session 1 | 14 days after inclusion |
| the full achievement of copy spelling and free spelling tests session 2 | 28 days after inclusion |
Countries
France
Contacts
Primary ContactClaude DESNUELLE, Pr
Outcome results
None listed