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Effects of Motive-Oriented Therapeutic Relationship in the Early-Phase Treatment of Borderline Personality Disorder

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01896024
Acronym
MOTR
Enrollment
85
Registered
2013-07-11
Start date
2010-06-30
Completion date
2014-04-30
Last updated
2014-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Borderline Personality Disorder

Brief summary

The present research aims at examining the effectiveness of a specific set of therapist relational interventions and attitudes, called the Motive-Oriented Therapeutic Relationship (MOTR), based on Plan Analysis (Caspar, 2007) in the early-phase treatment of patients diagnosed with Borderline Personality Disorder. The investigators intend to include N = 80 outpatients diagnosed with Borderline Personality Disorder, consulting at the Outpatient Personality Disorder Program of the Karl Jaspers Clinical Unit, in collaboration with the Institute of Psychotherapy, at the Department of Psychiatry-CHUV, University of Lausanne and in collaboration with the University of Berne, Switzerland. Patients are assigned by chance to two treatment conditions 1) Control condition (General Psychiatric Management; Gunderson & Links, 2008) and 2) MOTR-condition. The investigators hypothesize better results in the MOTR-condition, as compared to the control condition in terms of symptom reduction pre-post. The conduct of the study represents a significant contribution to the understanding and enhancement of relationship aspects in the treatment of patients diagnosed with Borderline Personality Disorder which may be of potential benefit for these patients.

Interventions

BEHAVIORALMotive-oriented therapeutic relationship/Plan Analysis

Sponsors

University of Lausanne Hospitals
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* DSM-IV Borderline Personality Disorder; * between 18 and 65 yrs of age

Exclusion criteria

* DSM-IV psychotic disorders, * mental retardation, * substance abuse in the forefront

Design outcomes

Primary

MeasureTime frameDescription
Outcome Questionnaire -45.2 (Lambert et al., 2004)3 monthspre- post- intervention in a randomized controlle trial; measure of symptom reduction over 3 months

Secondary

MeasureTime frameDescription
Inventory of Interpersonal Problems (Horowitz et al., 1988)3 monthsMeasure of interpersonal problems after 3 months of therapy

Other

MeasureTime frameDescription
Borderline Symptom List (Bohus, 2009)3 monthsSymptom reduction of borderline symptoms over 3 months of treatment

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 24, 2026