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Comparison of Gonioscopy With Cirrus and Visante

Comparison of Visante and Cirrus Optical Coherent Tomography for Assessment of the Anterior Segment

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01895686
Acronym
ASOCT
Enrollment
54
Registered
2013-07-10
Start date
2011-11-30
Completion date
2012-11-30
Last updated
2018-04-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Angle Closure Glaucoma, Narrow Angles, Open Angle Glaucoma

Keywords

open angle glaucoma, narrow angles, angle closure glaucoma, gonioscopy, anterior segment OCT

Brief summary

The aim of this study is to analyze similarities and evaluate interchangeability of Visante and Cirrus OCT (optical coherent tomography)and to compare agreement between gonioscopy and the two systems for evaluation of anterior segment parameters.

Detailed description

All participants underwent routine ophthalmic examination by their physician. Three independent examiners performed gonioscopy using Spaeth Gonioscopic Grading System. Findings were recorded independently along with risk assessment of angle being closed as: high, medium, and low or no risk. Patient information was not available to doctor during gonioscopy. One eye of each patient was imaged using both Visante and Cirrus OCT. Imaging was performed under scotopic and photopic conditions and obtained from horizontal (3:00 and 9:00 o'clock) and vertical (6:00 and 12:00 o'clock) meridians. The same experienced independent examiner performed all Cirrus measurements. Visante was performed by 3 trained technicians using same protocol. OCT images were exported and masked to be evaluated for presence of open or closed anterior chamber angle. Masked images were presented with no other patient information available to two examiners with glaucoma training working together to score on basis of iridocorneal angle as, closed (0 degree), high possibility (10 degree), medium risk (20 degree), and low or no risk (\> 30 degree).

Interventions

None listed

Sponsors

Wills Eye
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

• 18 years of age and older with open angle, narrow angle and angle closure

Exclusion criteria

• All lasers or intraocular surgery (cataract, glaucoma, retina, cornea)

Design outcomes

Primary

MeasureTime frameDescription
anterior angle measurement1 daycomparison of AS assessment by Cirrus, Visante, gonioscopies

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026