Biological Dressings
Conditions
Keywords
Laser therapy, Biological dressing, Amniotic membrane, Hydrocolloid bandages, wound healing
Brief summary
Bovine amniotic membrane may show better efficacy than hydrocolloid dressing.
Detailed description
Bovine amniotic membrane as a biological dressing can be applicable to wound after laser treatments. Comparing with hydrocolloid dressing material, which is the most widely used after laser treatment now, amniotic membrane will show better efficacy. Thus, with amniotic membrane, epithelization time will shorten and redness which is usually left after laser will disappear quickly.
Interventions
Sponsors
Seoul National University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
19 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* Skin lesions treatable by ablative lasers * More than two skin lesions of similar size at the same area * Available during the study period (2 weeks)
Exclusion criteria
* Taking steroid or nonsteroidal antiinflammatory drug, isotretinoin * underlying diabetes mellitus, keloid or any malignancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Epithelization time | 2 weeks | time to complete epithelization after wounding |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Photometric measurements | 2 weeks | spectrophotometer and colorimeter |
| Vancouver scar scale | 2 weeks | Vancouver scar scale |
| Epithelization Scale | 2 weeks | Assessment of redness, oozing, swelling |
| measurements of adverse effects | 2 weeks | assessments of adverse effects by investigator |
| histopathologic analysis | 2 weeks | changes of the tissue with time |
| Assessment by subjects | 2 weeks | pain, itching, inconvenience |
Countries
South Korea
Outcome results
None listed