Influence of Trigger Threshold on Controlled Twitch Mouth Pressure

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01891942

Enrollment

Registered

2013-07-03

Start date

2012-06-30

Completion date

2013-06-30

Last updated

2013-07-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COPD, Healthy

Keywords

Normal, subjects

Brief summary

The inspiratory pressure trigger is essential when assessing the twitch mouth pressure (Tw Pmo) for avoiding glottic closure. However, the difference in inspiratory pressure trigger threshold may influence the values of Tw Pmo. We sought to determine the trigger threshold for healthy subjects and COPD patients.

Interventions

PROCEDUREtwitch by magstim

Study design

Allocation

RANDOMIZED

Intervention model

FACTORIAL

Primary purpose

DIAGNOSTIC

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

MALE

Age

18 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

1. Clinical diagnosis of COPD 2. Stable with no episodes of exacerbation within the previous 2 months 3. Do not currently being treated with oral corticosteroids

Exclusion criteria

1. Not stable within the previous 2 months. 2. Patients with COPD were currently being treated with oral corticosteroids

Design outcomes

Primary

Measure	Time frame
Twitch mouth pressure	2 weeks

Secondary

Measure	Time frame
Twitch oesophageal pressure	2 weeks

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026