Study the Safety and Efficacy of Probiotics Use in Premature Infants

Status

Withdrawn

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01891604

Enrollment

Registered

2013-07-03

Start date

Unknown

Completion date

Unknown

Last updated

2017-05-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infant, Premature, Diseases

Brief summary

Prophylactic enteral probiotics may enhance clinical markers and biomarkers of preterm infants' health, and may also play a role in reducing NEC and associated morbidity.

Interventions

DIETARY_SUPPLEMENTbreast milk with Bifidobacterium Longum subp. Infantis R0033

DIETARY_SUPPLEMENTbreast milk

Study design

Intervention model

PARALLEL

Eligibility

Sex/Gender

ALL

Age

No minimum to 2 Days

Healthy volunteers

Yes

Inclusion criteria

* born with weight\<1500 g * hospitalized within 48 hours after birth

Exclusion criteria

* present with evidence or suspicion of congenital intestinal obstruction * perforation * gastroschisis * large omphalocele * congenital diaphragmatic hernia * major congenital heart defects

Design outcomes

Primary

Measure	Time frame
Calprotectin will be used to determine the effect for probiotics	day1 and day30 of the observation

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026