Heart Failure, Renal Failure, Respiratory Failure, Sepsis
Conditions
Keywords
cardiac output, mechanical ventilation, inert gas rebreathing, pulse contour analysis
Brief summary
Measuring hemodynamic parameters in ventilated patients is important yet still complicated to perform. Inert gas rebreathing (IGR) showed promising results when being compared to other invasive as well as non-invasive techniques for the measurement of cardiac output. The aim of our study is to evaluate the feasibility of IGR in ventilated patients.
Interventions
DEVICEnon-invasive determination of cardiac output
Sponsors
Universitätsmedizin Mannheim
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* age 18 - 80 years * mechanically ventilated patient * existing PiCCO arterial line
Exclusion criteria
* FiO2 \> 60% (fraction of inspired oxygen) * PEEP \> 10 mmHg (positive end-expiratory pressure) * SO2 \< 90% (oxygen saturation ) * Systolic blood pressure \< 90 mmHg * Heart rate \> 150 bpm * APRV (airway pressure release ventilation) * ICD (implantable cardioverter defibrillator) / pace maker * \[ Anaesthetic Conserving Device (Anaconda) \]
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| cardiac output | 1 day | Determination of cardiac output using invasive pulse contour analysis (PiCCO) and non-invasive inert gas rebreathing (Innocor) |
Countries
Germany
Outcome results
None listed