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Assessment of Acute Renal Injury During Partial Nephrectomy Using Neutrophil Gelatinase-associated Lipocalin (NGAL): Prospective Comparative Study Between Open, Video-assisted Minilaparotomy, Laparoscopic, and Robotic-assisted Laparoscopic Surgery

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01891032
Enrollment
160
Registered
2013-07-02
Start date
2013-06-30
Completion date
2014-05-31
Last updated
2014-07-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

the Patients With Partial Nephrectomy

Keywords

acute kidney injury, partial nephrectomy, biomarker

Brief summary

Urinary Neutrophil gelatinase associated lipocalin (NGAL) has been recently reported to be related with the degree of acute kidney injury. We are trying to analyze whether it is related with the grade of acute kiney injury after partial nephrectomy and there is any difference between the kinds of surgery.

Interventions

None listed

Sponsors

Yonsei University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No

Inclusion criteria

1. adults patient more than 20 years old with ASA score 1-3 2. the patients who undergoing partial nephrectomy for the renal mass less than 7 cm

Exclusion criteria

1. the patient with previous history with renal surgery 2. the patient with bilateral partial nephrectomy 3. the patient with synchronous operation for other intraperitoneal surgery 4. the renal mass more than 7 cm 5. previous kinds of surgery is changed into other kinds due to bleeding, etc 6. the patient with serum Cr level more than 1.4 mg/dl 7. the patient who does not understand the consent form

Design outcomes

Primary

MeasureTime frameDescription
The level of urinary NGALchanges from Preoperative, postop 3hr, 24hr, 48hrs after partial nephrectomyAnalysis of correlation between the level of preoperative and postoperative urinary NGAL

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026