Constipation, DMD
Conditions
Brief summary
In this research study the investigators want to screen Duchenne Muscular Dystrophy (DMD) patients for signs and symptoms of constipation in patients over 18. The investigators hypothesized: * DMD patients have a high prevalence of constipation than in the general population. * Prevalence of constipation will increase with age and with worsening functional status.
Detailed description
The following procedures will take place during the study. Constipation Assessment: * The patient will be asked to complete a questionnaire about any symptoms of constipation. * A physician from the study team will perform an abdominal physical exam * The patient will have routine x-rays that monitor for spine compression fractures. These films will also be used to assess stool content. Clinical Information The following information will also be collected during the clinic visit ; * Age at diagnosis and genetic mutation * Age at loss of ambulation if applicable * Medications * Functional status
Interventions
DEVICESmartPill ingestion
The participant would ingest the SmartPill and wear the data receiver for up to 5 days.
Sponsors
Children's Hospital Medical Center, Cincinnati
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
MALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients with a diagnosis of Duchenne Muscular Dystrophy (based on clinical presentation and verified by compatible muscle biopsy or known dystrophin gene mutation). * Age greater than or equal to 18 years old
Exclusion criteria
* None
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| GI transit times | up to 5 days | Gi transit times will be computed by an investigator. |
Countries
United States
Outcome results
None listed