Bariatric Surgery
Conditions
Brief summary
During minimally invasive surgery, a pneumoperitoneum is created to facilitate surgical visualization. Although effective in facilitating the procedure, there are respiratory consequences of the pneumoperitoneum, which significantly increases intra-abdominal pressure (IAP) up to 20 cmH2O. The increased IAP can decrease functional residual capacity and increase closing capacity resulting in increased resistance, decreased compliance, and increased ventilation-perfusion mismatch. In a randomized, cross-over design, this study will evaluate in sequential order, 3 modes of ventilation during laparoscopic bariatric surgery to determine which is better able to support oxygenation and ventilation while limiting the peak inflating pressure (PIP).
Interventions
For pressure controlled ventilation, the peak inflating pressure (PIP) is set for each tidal breath.
For volume controlled ventilation, the tidal volume is set.
OTHERPRVC ventilation
Pressure-regulated, volume-controlled (PRVC) is an auto-regulated pressure-controlled mode of mechanical ventilation with a user-selected tidal volume target.
Sponsors
Joseph D. Tobias
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
14 Years to 20 Years
Healthy volunteers
No
Inclusion criteria
* Laparoscopic bariatric surgery requiring intra-arterial blood pressure monitoring, age 14-20 years.
Exclusion criteria
* None
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in heart rate | Baseline to 30 mins. | Heart rate will be assessed every 5 mins. during each 30 minute mode of ventilation. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in blood pressure | Baseline to 30 mins. | Blood pressure will be recorded every 5 mins. during each 30 minute mode of ventilation. |
| Blood gas | 30 mins. | Blood gas will be obtained at the end of each 30 minute mode of ventilation. |
Countries
United States
Outcome results
None listed