Mixed Anxiety Disorders
Conditions
Keywords
MCT, Metacognitive therapy, Anxiety disorders, Transdiagnostic
Brief summary
Comorbidity is normal in clinical practice. Metacognitive Therapy (MCT) is a transdiagnostic model and could therefore be well suited when it comes to treating patients with high rates of comorbidity. So far, no studies have examined MCT in comparison with the best documented and evidence based treatment, cognitive behavioral treatment(CBT), in a randomized controlled trial consisting of mixed anxiety disorder sample with high degree of comorbidity. The main aim of this study is to 1) Evaluate the effectiveness of metacognitive therapy in a sample of mixed anxiety disorders as compared to a group receiving existing evidence-based single diagnosis CBT- treatment protocols 2) Investigate patterns and mechanisms of change in the two treatments.
Interventions
BEHAVIORALMetacognitive therapy
BEHAVIORALCognitive behavioral therapy
Sponsors
Modum Bad
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* DSM IV diagnoses of SAD, PD/A or PTSD (CSR\>4) * Withdraw of all psychotropic medications before treatment
Exclusion criteria
* Psychosis * Not willing to accept randomization * Comorbid conditions are in immediate need of treatment
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Anxiety Disorders Interview Schedule for DSM-IV-Lifetime Version | PRE/POST/1 year follow up | The ADIS -IV is a semistructured diagnostic interview designed to establish reliable DSM-IV anxiety, mood, somatoform and substance disorders. Interviewers assign a 0-8 clinical severity rating (CSR), that indicate their judgement of the degree of distress. |
| Beck Anxiety Inventory (BAI) | PRE/POST/weekly and 1 year follow up | — |
Secondary
| Measure | Time frame |
|---|---|
| Metacognitions Questionnaire- 30 (MCQ-30; Wells & Cartwright-Hatton, 2003) | Pre/Post/weekly and 1 year follow up |
| Working Alliance Inventory (WAI; Horwath & Greenberg, 1989) | Pre/Post/weekly and 1 year follow up |
| Cognitive attentional syndrome 1 (CAS1; Wells, 2009) | Pre/Post/weekly and 1 year follow up |
| The Repetitive Thinking Questionnaire(RTQ; McEvoy et al., 2010) | Pre/Post and 1 year follow up |
| PTSD Symptom scale Self Report (PSSR; Foa et al., 1993) | Pre/Post and 1 year follow up |
| Social Phobia Inventory (SPIN; Connor et al., 2000) | Pre/Post and 1 year follow up |
| The Symptom Checklist 90(SCL90; Derogatis et al., 1996) | Pre/Post/1 year follow up |
| SF 36 | Pre/Post and 1 year follow up |
| The Penn State Worry Questionnaire (PSWQ; Meyer, Miller, Metzger & Borkovec, 1990) | Pre/Post and 1 year follow up |
| Youngs Schema Questionnaire YSQ -75 (Young, 1998) | Pre/Post and 1 year follow up |
| The Inventory of Interpersonal Problems (IIP 64 C; Horowitz et al., 1988) | Pre/Post and 1 year follow up |
| Dysfunctional emotion regulations scale (DERS; Graz & Roemer, 2004) | Pre/Post/ and 1 year follow up |
| Mobility inventory (MI; Chambless, 1985) | Pre/Post and 1 year follow up |
| The Patient Health Questionnaire depression module (PHQ 9; Spitzer et al., 1999) | Pre/Post and 1 year follow up |
Countries
Norway
Outcome results
None listed