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Obesity and Mortality

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01889225
Enrollment
311982
Registered
2013-06-28
Start date
2008-01-31
Completion date
2013-12-31
Last updated
2014-08-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity and Overweight

Brief summary

Previous analyses of the National Health and Nutrition Examination Survey have suggested that the mortality rate associated with obesity has decreased over calendar time in the U.S. population, potentially due to improvements in the medical care of obesity and its associated diseases. The primary aim of this project is to evaluate whether this reduction in the detrimental association of obesity with mortality rate over calendar time is supported by other data from U.S. prospective studies.

Interventions

None listed

Sponsors

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
CollaboratorNIH
University of Alabama at Birmingham
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* U.S. based studies with at least 1500 subjects * At least 5 years of mortality follow-up * BMI measured or self-reported available at 2 or more separate calendar time * Subjects varied in age at baseline

Exclusion criteria

* Any study that does not meet the inclusion criteria was excluded

Design outcomes

Primary

MeasureTime frame
Change in Years of Life Lost Associated with Standard BMI categories Over Calendar TimeBetween 1960 and 2000 (up to 40 years)

Secondary

MeasureTime frame
Change in Adjusted Hazard Ratio Over Calendar Time for Standard BMI CategoriesBetween 1960 and 2000 (up to 40 years)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026