Body Mass Index Quantitative Trait Locus 7 Disorder, Tangier Disease
Conditions
Brief summary
The investigators aimed to determine the effects of HP diet on CVD risk factors among overweight and obese children.
Detailed description
Background: Studies regarding the effects of high protein (HP) diet on cardiovascular (CVD) risk factors have reported contradictory results. Objective: In present study, the investigators aimed to determine the effects of HP diet on CVD risk factors among overweight and obese children. Design: In this randomized controlled trial, the investigators recruited 50 overweight and obese women, aged 6-11years into HP or control energy restricted diets for 10 weeks (protein, carbohydrate, fat: 25%, 45%, 30% vs. 15%, 55%, 30%, respectively). Total protein amount, divided to animal and plant sources in 50%-50% and animal sources distributed (half/half) between meats and dairy products. Fasting blood samples, lipid profile, systolic and diastolic blood pressure and anthropometric measurements were measured based on the standard guidelines.
Interventions
OTHERnutrition intervention
high protein diet
Sponsors
Isfahan University of Medical Sciences
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
6 Years to 11 Years
Healthy volunteers
Yes
Inclusion criteria
* BMI \> 85th age of 6-11 years * no history of chronic diseases * no taken medications
Exclusion criteria
* do not prescribe their diet * mental retardation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the amount of weight reduction in two dietary groups | 10 weeks | weight reduction (kg) |
Secondary
| Measure | Time frame |
|---|---|
| LDL (mg/ml) | 10 weeks |
| HDL (mg/ml) | 10 weeks |
| fasting blood glucose | 10 weeks |
| total cholesterol (mg/dl) | 10 weeks |
| blood pressure | 10 weeks |
Countries
Iran
Outcome results
None listed