IOP Lowering Effect of PLT Versus SLT in Naiv OAG Patients

Effect of Patterned Laser Trabeculoplasty on Intraocular Pressure Compared to Selective Laser Trabeculoplasty in Treatment Naiv Patients Suffering From Open-angle Glaucoma or Ocular Hypertension

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01886456

Enrollment

210

Registered

2013-06-25

Start date

2013-02-28

Completion date

2017-02-28

Last updated

2013-06-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Open Angle Glaucoma,, Ocular Hypertension

Brief summary

To investigate the effect of patterned laser trabeculoplasty (PLT) compared to selective laser trabeculoplasty (SLT) on intraocular pressure (IOP) in treatment naiv patients suffering from open-angle glaucoma or ocular hypertension. Values for IOP will be measured at baseline, 1 day and 1 month post-interventional as well as 2, 3, 6, 9, 12, 18 and 24 months after treatment. * Trial with medical device

Interventions

DEVICELaser trabeculoplasty

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Intraocular pressure (treatment naiv or after 4 weeks wash-out phase) \> 21 mm Hg * visible angle structures over 360° on gonioscopy * age = 18 years

Exclusion criteria

* Intraocular Inflammation * patients who underwent refractive corneal surgery for any reason or who underwent ocular surgery to reduce intraocular pressure (e.g. trabeculectomy) * monocle situation * anterior chamber lenses (incl. iris claw) * secondary glaucoma (with the exception of pseudoexfoliation and pigment dispersion)

Design outcomes

Primary

Measure	Time frame
Intraocular pressure 6 months after Intervention	6 months

Countries

Switzerland

Contacts

Primary ContactGregor Jaggi, MD

gregor.jaggi@usz.ch

Backup ContactChristoph Kniestedt, MD

christoph.kniestedt@usz.ch

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026