Platelet Function, Pregnancy
Conditions
Keywords
pregnancy, platelet function, monitoring, multiple electrode aggregometry
Brief summary
Establishment of a range of normal values in pregnancy with the Multiple Electrode Aggregometry (Multiplate@) device, a device that allows measurement of not only platelet count but platelet function. This has not been studied in ths special patient group. Results from this trial will be used as a basis for further investigation of abnormal platelet function in pregnancy.
Interventions
OTHERPlatelet function during pregnancy Multiple Electrode Aggregometry (Multiplate@) device
Observation of platelet function in pregnancy
Sponsors
Medical University of Vienna
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* pregnancy
Exclusion criteria
* Rejection of informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change of platelet function | 4x, as specified below | Measurement of change of platelet function by the Multiplate® device. First measurement (baseline measurement) at enrollment into the trial. Second measurement during government-mandated gynaecological evaluation, around the 20th week of pregnancy. Third measurement immediately prior to delivery. Last measurement one week after delivery. 2nd, 3rd and 4th measurement for assessment of change from baseline. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Platelet-associated complications | 4x, as specified below (baseline, 20th week) | Record of bleeding events, preeclampsia, HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome. Time points: at every assessment of primary outcome measure, as described above. |
Countries
Austria
Contacts
Primary ContactReinhard Hahn, MD
Backup ContactAlbert M de Bettignies
Outcome results
None listed