Bioavailability of Potassium From Potatoes and Potassium Gluconate

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01881295

Acronym

Potato

Enrollment

Registered

2013-06-19

Start date

2013-03-01

Completion date

2014-12-31

Last updated

2018-05-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood Pressure, Potassium Bioavailability

Keywords

Potassium, Potato, French Fries, Bioavailability, Blood Pressure

Brief summary

This study is designed to compare the effect of sources of potassium on uptake and the effect of potassium on blood pressure.

Detailed description

The study will compare uptake of potassium from three different doses and sources; supplements (720, 1440 and 2160 mg) potatoes (720, 1440 and 2160 mg) or French fries (2160 mg). During 9 phases, participants will consume a controlled diet with the supplements, potato or french fries (every other week for 5 days). On the 4th day, blood and urine samples will be taken to monitor potassium uptake and excretion. Measures of blood pressure will be analyzed at defined time points throughout the intervention.

Interventions

DIETARY_SUPPLEMENTPlacebo control

DIETARY_SUPPLEMENTLow dose potassium gluconate

DIETARY_SUPPLEMENTMedium dose potassium gluconate

DIETARY_SUPPLEMENTHigh dose potassium gluconate

DIETARY_SUPPLEMENTLow dose potato

DIETARY_SUPPLEMENTMedium dose potato

DIETARY_SUPPLEMENTHigh dose potato

DIETARY_SUPPLEMENTHigh dose French fries

DIETARY_SUPPLEMENTBasal diet control

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

OTHER

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

20 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* Able to adhere to the visit schedule, protocol requirements and available to complete the study * Normotensive men and women * Aged 20-60 years * BMI of 15-35

Exclusion criteria

* Medication to treat hypertension or hypotension * Medication known to affect electrolyte metabolism or contain high levels of potassium or sodium * smoke cigarettes or use illegal drugs * Hypertension or hypotension * Diseases known to affect potassium metabolism * Pregnant * Allergic to nuts

Design outcomes

Primary

Measure	Time frame	Description
Bioavailability of Potassium	5 days	After 4 days of acclimation to the supplementation, absorption of potassium will be measured.

Secondary

Measure	Time frame	Description
Blood Pressure Response to Potassium	6 days	Differences in blood pressure will be measured between levels of potassium consumption.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 12, 2026