The BabyGrow Longitudinal Study of Nutrition and Growth in Preterm Infants

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01881256

Acronym

BabyGrow

Enrollment

Registered

2013-06-19

Start date

2010-03-31

Completion date

2011-10-31

Last updated

2013-06-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malnutrition; Intrauterine or Fetal, Small-for-dates, Premature Birth of Newborn

Keywords

Preterm birth, Parenteral and enteral nutrition, Body composition in preterm infants

Brief summary

This is a longitudinal, observational study on nutrition, growth and body composition in preterm infants. Aims to determine the adequacy of actual nutrient intake during the preterm period by investigating associations between macronutrient supply, growth, and body composition at 34-weeks gestation, term equivalent and 2-month corrected gestational age.

Detailed description

Infants between 23 and 24 weeks gestation and with a birth weight of 500 to 1500 g are recruited to a longitudinal, observational study of nutrition, growth and body composition in Cork University Maternity Hospital, Ireland.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

No minimum to 34 Weeks

Healthy volunteers

Inclusion criteria

* Babies with a birth weight ≤1.5kg and gestational age ≤34 weeks were considered eligible.

Exclusion criteria

* presence of congenital abnormalities or conditions that interfere with growth or body composition (congenital diseases, chromosomal abnormalities, chronic lung disease, cardiac or gastrointestinal diseases).

Design outcomes

Primary

Measure	Time frame	Description
Actual nutrient intake vs recommended nutrient requirements in preterm infants	19 months	Comparison of intake with requirements during the preterm infant's hospital stay and up to 2 months corrected gestational age.

Secondary

Measure	Time frame	Description
Longitudinal data on body composition in Irish preterm neonates	19 months	Evaluation of appropriateness of current feeding regimens for achievement of optimal growth & body composition outcomes
Longitudinal data on vitamin D intake and circulating 25(OH)D	19 months	To examine the relationship between vitamin D intake and serum 25-hydroxyvitamin D concentrations and biomarkers of calcium handling by analysis of sequential serum samples.

Outcome results