Relieve of Ureteral Stent Symptoms
Conditions
Keywords
Double J, Ureteral stents, Symptoms, Alpha blockers, Anticholinergic
Brief summary
This study will be conducted to compare the effectiveness of alpha blocker (Tamsulosin) and Anticholinergic (Solifenacin) in relieving lower urinary tract symptoms caused DJ ureteral stents.
Detailed description
Eligible patients who signed the informed consent will randomly assigned to one of 3 groups; group 1 (control), group 2 (tamsulosin) and group 3 (Solifenacin). Ureteral stent symptom questionnaire (USSQ) will be used to compare health related quality of life scores.
Interventions
DRUGTamsulosin
Patients in this arm will receive Tamsulosin 0.4 mg daily
DRUGSolifenacin
Patients in the arm will receive Solifenacin
DRUGControl
Patients in this are will receive placebo
Sponsors
Mansoura University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
Patient who will undergo unilateral ureteral stent fixation: 1. To relieve upper urinary tract obstruction caused by ureteric calculi 2. After ureteroscopic lithotripsy for ureteral calculi.
Exclusion criteria
1. Patients who had LUTS before stent fixation. 2. Ureteral stent fixation after open or laparoscopic surgery. 3. Bilateral ureteral stents. 4. Patients who developed complications related to the primary endoscopic procedure 5. Patients who developed stent related complications such as hematuria, acute pyelonephritis or stent displacement
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The Efficacy of tamsulosin and solifenacin in relieving ureteral stent symptoms will be evaluated by comparing the scores of ureteral stent symptoms questionnaire in the studied groups | 1 year |
Countries
Egypt
Outcome results
None listed