Effective Rehabilitation of Patients Operated With Total Knee Arthroplasty

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01877733

Enrollment

Registered

2013-06-14

Start date

2013-01-31

Completion date

2015-07-31

Last updated

2020-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis

Keywords

Resistance training

Brief summary

The purpose of this study is to investigate the effect of maximal strength training (MST) compared to standard rehabilitation in patients operated with total knee arthroplasty. Previous studies report reduced physical function and muscle strength despite successful surgery inserting an artificial implant. Furthermore, great loss of muscle strength has been found in these patients in the early postoperative phase. The study is a randomized controlled trial. The investigators hypothesize that MST will increase muscle strength and physical function more than standard rehabilitation.

Interventions

OTHERMaximal strength training

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

* unilateral osteoarthritis, * \< 75 years

Exclusion criteria

* disease(s) that compromise testing/training, * unable to understand written and verbal instructions and information, * osteoarthritis in the contralateral leg that needs treatment.

Design outcomes

Primary

Measure	Time frame	Description
Muscle strength in leg extension and leg press	Measured preoperatively, after 7 days, 10 wks and 1 year	Measured preoperatively implies measuring the outcome within the last month prior to surgery

Secondary

Measure	Time frame	Description
EQ-5D (measure of health outcome)	Preoperatively (within 1 month prior to surgery), 7 days, 10 wks and 1 year postoperatively	—
VAS scale recording pain	preoperatively (within 1 month prior to surgery), 7 days, 10 wks and 1 year postoperatively	—
6 minute walk test	preopertively, 7 days postoperatively and after 1 year	Measuring the outcome preoperatively implies testing within the last month prior to surgery
KOOS; Knee injury and osteosarthritis outcome score	Preoperatively (within 1 month prior to surgery), 7 days postoperatively and 10 wks and 1 year postoperatively	—

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026