Iron Absorption From GDS Capsules

Iron Absorption Mechanism From a Slow Release Iron Capsule Using the Gastric Delivery System

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01874496

Enrollment

Registered

2013-06-11

Start date

2013-05-31

Completion date

2013-08-31

Last updated

2013-09-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Iron Deficiency

Brief summary

Slow release iron capsules have been designed based on the gastric delivery system. Iron absorption from those capsules administered with and without meals will be measured using stable iron isotopes.

Interventions

DIETARY_SUPPLEMENTGDS, no meal

GDS, no meal

DIETARY_SUPPLEMENTGDS, meal

GDS, meal

DIETARY_SUPPLEMENTcontrol, no meal

control, no meal

DIETARY_SUPPLEMENTcontrol, meal

control, meal

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

BASIC_SCIENCE

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* female, * age 18-50 years, * max. body weight 65 kg, * serum ferritin \< 35µg/l

Exclusion criteria

* pregnancy, * lactation, * regular intake of medication, * blood donation or significant blood losses over the past 4 months

Design outcomes

Primary

Measure	Time frame
fractional iron absorption	2, 4, 6, and 8 weeks

Secondary

Measure	Time frame
serum isotope appearance	day 1, 15, 29 and 33

Other

Measure	Time frame
Serum non transferrin bound iron	day 1, 15, 29 and 33

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026