Implication of Left veNtricle Vortex Flow Guided aNticOagulation Therapy for preVenting Apical Thrombus Formation In Patients With Acute myOcardial infarctioN: Multicenter Prospective Randomized Clinical Trial; INNOVATION Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01869998

Enrollment

111

Registered

2013-06-05

Start date

2012-02-29

Completion date

2015-09-30

Last updated

2016-05-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Myocardial Infarction, Apical Thrombus Formation

Keywords

Vortex, Thrombus, Contrast echocardiography, Prediction and prevention of apical thrombus formation in acute myocardial infarction patient by using Vortex parameters.

Brief summary

Implication of left veNtricle vortex flow guided aNticOagulation therapy for preVenting Apical Thrombus formation In patients with acute myOcardial infarctioN: Multicenter Prospective Randomized Clinical Trial; INNOVATION study

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

30 Years to 90 Years

Healthy volunteers

Inclusion criteria

1. Patient is ≥ 30 years old 2. Acute anterior wall myocardial infarction showing akinetic or dyskinetic apical wall motion abnormalities on an initial transthoracic echocardiogram 3. Left ventricular ejection fraction less than 40%

Exclusion criteria

1. Prior history of myocardial infarction 2. Chronic medication with Coumadin 3. Contraindication of contrast echocardiography 4. Significant atrial or ventricular arrhythmia 5. Valvular heart disease more than moderate degree 6. Decompensated heart failure 7. Very poor echo window, which cannot evaluate the presence of apical thrombus

Design outcomes

Primary

Measure	Time frame	Description
Apical thrombus formation in echocardiography	30 days after initial echocardiography	Evaluate and compare the incidence of thrombus formation in high risk group (Vortex depth \< 0.45) and low risk group (Vortex Depth ≥ 0.45)

Countries

South Korea

Outcome results