Postpartum Screening of Type 2 Diabetes

Can we Screen Type 2 Diabetes on the 2nd Day After Delivery in Women Who Had Gestational Diabetes Mellitus?

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01869608

Acronym

Tot ou tard

Enrollment

121

Registered

2013-06-05

Start date

2014-04-30

Completion date

2018-12-31

Last updated

2019-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 Diabetes

Keywords

postpartum screening, type 2 diabetes

Brief summary

Gestational diabetes mellitus (GDM) complicates 5 to 30 % of pregnancies. GDM is defined as hyperglycemia with onset or first recognition during pregnancy. Because it is a forerunner of type 2 diabetes mellitus (T2DM), professional associations recommend T2DM postpartum screening (T2DM-pPS) at 6 weeks/6 months post delivery, using a 75g oral glucose tolerance test (OGTT). However, less than a quarter of these women are screened. This recommendation has failed for multiple reasons; the most important being that busy new mothers must deal with the major inconveniences of returning to a sampling center for a 2h testing session, bringing baby along or paying for a sitter, transportation, parking… A mother-friendly solution is direly needed. The investigators hypothesize that, in these women, results of an OGTT performed after delivery on the last day of their hospital stay (OGTT-1) will predict results of the recommended OGTT (OGTT-2) at 6 weeks/6 months postpartum. The main aim of our project is to determine the optimal cut-off value for the 2h glucose result during OGTT-1 in order to predict abnormal glucose tolerance status at OGTT-2 (the gold standard), in the same woman.

Interventions

PROCEDUREoral glucose tolerance test 2 days post-partum

Screening for type 2 diabetes after gestational diabetes mellitus.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 45 Years

Healthy volunteers

Inclusion criteria

* Women aged between 18 and 45 years; * Having a positive diagnosis of gestational diabetes mellitus (IADPSG criteria); * Treated with diet or insulin; * Have given birth to a child at term; gestational age \> 37 weeks; * Have been followed during her pregnancy by a physician who delivers in CHUS; * Have signed the consent form.

Exclusion criteria

* History of glucose intolerance or diabetes before the pregnancy; * Have presented another obstetrical pathology during the pregnancy; * Severe gestational high blood pressure with proteinuria; * Delayed intrauterine development syndrome; * Pregnancy with more than a foetus; * Drug addiction; * Had complications during the delivery such as: * Moderate to severe postpartum bleeding; * Surgery in postpartum (curettage, hysterectomy, etc.).

Design outcomes

Primary

Measure	Time frame	Description
Diagnosis of abnormal glucose tolerance	12 weeks postpartum	Oral glucose tolerance test

Secondary

Measure	Time frame	Description
Patient's satisfaction	12 weeks post-partum	Satisfaction questionnaire

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026