Ten-year Outcomes After AF Ablation

Long-term Outcome After Initially Successful Catheter Ablation of Atrial Fibrillation by Pulmonary Vein Isolation: a Ten-Year Cohort Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01867099

Enrollment

445

Registered

2013-06-03

Start date

2002-12-31

Completion date

2012-12-31

Last updated

2014-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial Fibrillation

Brief summary

Ablation of atrial fibrillation (AF) using pulmonary vein isolation is employed when patients do not respond favorably to medical therapy. Successful procedures are accomplished in the majority of patients, but the outcome after many years of follow-up after ablation is unknown.

Detailed description

A prospectively identified cohort of 445 patients who demonstrated freedom from AF for at least one year following ablation (single procedure in 391, 87.9%) was followed for 66.0 ± 34.0 months. Patients were seen at least annually as outpatients, and underwent regular ECG monitoring, especially if there were symptoms suggestive of recurrent arrhythmia. Continued absence of arrhythmia was defined as freedom from AF or flutter \> 30 secs.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 85 Years

Healthy volunteers

Inclusion criteria

* Prior AF ablation procedure * No AF for one year post ablation

Exclusion criteria

* Geographic inaccessibility * Longstanding persistent AF * Recurrent AF within one year of ablation * Prior AF ablation

Design outcomes

Primary

Measure	Time frame
Atrial fibrillation or flutter > 30 secs	More than one year after successful primary ablation or redo procedure within 6 mos

Countries

United States

Outcome results