Anxiety
Conditions
Keywords
anxiety, midazolam, forced-air warming
Brief summary
Patients are often anxious immediately before surgery. The investigators hypothesis is that a warming blanket is as effective as the sedative midazolam in allaying anxiety before surgery.
Detailed description
The investigators are randomising patients aged 18-70 having elective surgery to 1) a cotton blanket and reassurance as required; 2) midazolam, a cotton blanket and reassurance as required; and 3) forced-air warming, a cotton blanket and reassurance as required. The primary endpoint is a visual analog scale of anxiety.
Interventions
DRUGMidazolam
Intravenous midazolam 0.3 mg/kg
DRUGNormal Saline
Normal saline injection will be given to groups not receiving midazolam
DEVICEBair Hugger
Forced air warming
Sponsors
Melbourne Health
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Patients aged between 18 and 70 years * male and female * presenting for elective surgery * requiring general anaesthesia * ASA 1-3
Exclusion criteria
* Cardiothoracic and intracranial surgery * Day case surgery * Pre-existing anxiety disorder * Patients on psychotropic drugs preoperatively Febrile patients T \> 37.5 degrees Celsius Allergy to midazolam Obstructive Sleep Apnoea diagnosed on sleep study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analog scale score for anxiety | During immediate pre-operative phase |
Secondary
| Measure | Time frame |
|---|---|
| Thermal comfort | During immediate pre-operative phase |
| Recovery from anaesthesia | During immediate post-operative phase |
| Satisfaction with care | During immediate post-operative phase |
Countries
Australia
Outcome results
None listed