Orthodontic Malocclusion
Conditions
Keywords
orthodontics, Tooth Movement, Bone Remodeling, Mandible, Osteotomy
Brief summary
The purpose of this investigation is intended to evaluate the efficacy of surgically facilitated orthodontic treatment (SFO) in terms of treatment time, incidence of root shortening, and occurrence of mucogingival side effects compared to conventional orthodontic therapy in patients undergoing orthodontic treatment to correct crowding and/or retroclination of their mandibular anterior dentition.
Detailed description
The null-hypothesis for this research project is that there will be no difference in the rate of orthodontic movement among patients requiring proclination or alignment of their mandibular anterior teeth with SFO (TEST group) as compared to conventional orthodontic treatment (CONTROL group). A null-hypothesis is that there will be no difference between both treatment groups in the occurrence of dental (root shortening) or periodontal (mucogingival defects, alveolar bone resorption) complications associated with orthodontic treatment.
Interventions
PROCEDURESurgically facilitated Orthodontic treatment
Surgically facilitated Orthodontic treatment in the mandibular anterior region
PROCEDUREConventional orthodontic treatment
Conventional orthodontic Procedure
Sponsors
University of Minnesota
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
-Adults (18-65 y.o.) who seek orthodontic treatment for proclination and/or de-crowding of mandibular anterior teeth.
Exclusion criteria
* Bone-related diseases * Previous or current use of biphosphate therapy * Previous mucogingival surgery in the area * Genetic syndromes, craniofacial anomalies, or cleft lip and/or palate \- History of previous orthodontic treatment less than 4 years ago * Smoking \>10 cigarettes/day ) * Medical history that contraindicates surgical treatment, * People who are not cognitively able to give consent, * Pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Rate of orthodontic tooth movement | 6 months(plus or minus 1 week) | Difference between the rate of orthodontic tooth movement between the two groups as measured by linear measurements on digitized study casts obtained at 4-week intervals. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of mucogingival defects | 6 months(plus or minus 2weeks) after initiation of treatment | Incidence of mucogingival defects as clinically measured by gingival recession (GR), clinical attachment level (CAL), probing depth (PD), width of keratinized tissue (WKT) and biotype), by a calibrated examiner |
| Incidence and magnitude of apical root resorption | 6(plus or minus 1) months following initiation of treatment | Incidence and magnitude of apical root resorption will be estimated from pre- and post-treatment cone-beam computed tomograms (CBCTs) |
Other
| Measure | Time frame | Description |
|---|---|---|
| Thickness and height of the buccal and lingual bony plates | 6(plus or minus 1) months following initiation of treatment | Thickness and height of the buccal and lingual bony plates will be measured from pre- and post-treatment Cone beam volumetric tomograms |
Outcome results
None listed