Analgesia, Bowel Cancer Screening, Colonoscopy, Entonox
Conditions
Keywords
Bowel cancer screening, Analgesia, Entonox, Pain, Side effects, Colonoscopy
Brief summary
This study will randomise patients undergoing screening colonoscopy to receive Entonox either continuously or as required. Both these methods are used in the published studies of Entonox and in clinical practice. Null hypothesis There will be no difference in pain levels between these two methods of Entonox administration
Interventions
DRUGEntonox
Entonox will be used according to the allocated method
Sponsors
Sheffield Teaching Hospitals NHS Foundation Trust
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
60 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Having a bowel cancer screening programme colonoscopy
Exclusion criteria
* Contraindications to Entonox * Previous bowel resections
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pain scores | Day 1: Prior to discharge from endoscopy department | Patients will be asked about their overall recollection of pain on a 10 point numerical ratings scale prior to discharge |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pain scores | Day 1-4: Prior to discharge and 1-3 days later | Patients will be asked about their experience of pain during colonoscopy. In addition patients will be asked about their overall recollection of pain immediately after colonoscopy and 1-3 days following colonoscopy. |
| Use of analgesia and sedation | Day 1: During colonoscopy | Patients additional use of sedation and analgesia will be compared in each treatment arm |
| Patients satisfaction | Day 1-4: Prior to discharge and 1-3 days later | Patients will be asked about their overall level of satisfaction immediately prior to discharge and 1-3 days later |
| Willingness to have a repeat colonoscopy | Day 1: Prior to discharge | Patients will be asked about their willingness to have a repeat colonoscopy prior to discharge and 1-3 days following colonoscopy |
| Side Effects | Day 1: During colonoscopy | Patients will be asked about the presence of side effects during colonoscopy. This will be quantified according to whether it limited the use Of Entonox. |
Countries
United Kingdom
Outcome results
None listed