Hypertension, Obese
Conditions
Brief summary
The purpose of this study is to evaluate the effects of green tea on body weight, waist circumference, metabolic profile, inflammation, blood pressure and endothelial function in obese pre-hypertensive women.
Detailed description
Crossover randomized controlled double-blinded trial. Twenty women with obesity and pre-hypertension, aged 28-59 years, with stable body weight were randomized to receive a daily supplement of 3 capsules that contained either 500mg of green tea extract (GTE) or a matching placebo for 4 weeks, with a washout period of 2 weeks between the treatments. Endothelial function was evaluated by peripheral arterial tonometry method, using Endo-PAT 2000®.
Interventions
DIETARY_SUPPLEMENTGreen Tea
Twenty women with obesity and pre-hypertension, aged 28-59 years, with stable body weight were randomized to receive a daily supplement of 3 capsules that contained either 500mg of green tea extract (GTE) or a matching placebo for 4 weeks, with a washout period of 2 weeks between the treatments.
Sponsors
Rio de Janeiro State University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
SUPPORTIVE_CARE
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
28 Years to 59 Years
Healthy volunteers
Yes
Inclusion criteria
pre-hypertensive women obese adult
Exclusion criteria
pregnant smoker elderly
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction of blood pressure | 12 weeks |
Countries
Brazil
Outcome results
None listed