BHCG Level in Day 4,7, in Comparison to Day 10 as an Indicator for Treatment Success

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01860690

Acronym

BHCG

Enrollment

100

Registered

2013-05-23

Start date

2011-11-30

Completion date

2014-02-28

Last updated

2013-05-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ectopic Pregnancy

Keywords

MTX, Ectopic pregnancy, medical treatment

Brief summary

The investigators want to compeer BHCG levels after Methotrexate ( MTX). treatment for Ectopic pregnancy in days 4 and 7 after MTX. to day 10 . The hypothesis is that BHCG level in day 10 is the best indicator for treatment success , superior to day 4 and 7 . According to the investigators impression BHCG level rises in days 4 and 7 due to destruction of the trophoblast tissue , and only day 10 is an indicator for treatment success

Interventions

DRUGMethotrexate

50 mg / meter squer Intramuscular (IM) MTX.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* patients with ectopic pregnancy * healthy * hemodynamic stable * first ectopic

Exclusion criteria

* hemodynamic non-stable * abnormal liver or kidney function * allergy reaction to MTX

Design outcomes

Primary

Measure	Time frame	Description
To measure the change of levels of BHCG in patients receiving Methotrexate for treatment of ectopic pregnancy in days 4, 7, and 10 post treatment	the change of levels in days 4, 7, and 10 post MTX injection	To compeer levels of BHCG in days 4 and 7 to day 10 after injection of MTX. for Ectopic pregnancy treatment

Countries

Israel

Contacts

Primary ContactZvi Klein, Dr.

kleinz@clalit.org.il972-9-7472544

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026