Meshed Vein Graft Patency Trial - VEST

External Mesh of Vein Grafts In Coronary Artery Bypass Grating: Early Patency and Clinical Outcome

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01860274

Enrollment

102

Registered

2013-05-22

Start date

2015-09-06

Completion date

2020-06-28

Last updated

2021-03-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease

Keywords

Mesh, Graft, Patency

Brief summary

The study hypothesis is that a meshed conduit made of safen vein allows a better patency at mid-long term than a safen vein alone. To test this hypothesis the investigators plan a prospective, randomized study, comparing grafts to the diagonal, in cases of vessel diameter under 1.5mm. A control angiography will be performed one year after the operation.

Interventions

DEVICEExternal Mesh for vein grafts

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Clinical Indication for elective Coronary Artery Bypass Grafting with at least one vein graft * Coronary artery with critical stenosis (over 70%)

Exclusion criteria

Design outcomes

Primary

Measure	Time frame	Description
Patency	6 to 12 months	Patency of graft at CT Scan

Secondary

Measure	Time frame
Major Adverse Cardiac and Cerebrovascular Events (MACCE)	60 months
Vein graft lumen uniformity	6 to 12 months

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 23, 2026