Other Acute Postoperative Pain
Conditions
Keywords
Pediatric spinal anesthesia, paracetamol, dipyrone
Brief summary
We conducted a prospective, randomized double-blind study to compare the effectiveness of intravenous paracetamol and dipyrone for preventing pain during early postoperative period in school-age children undergoing lower abdominal surgery with spinal anesthesia.
Detailed description
The intensity of postoperative pain was assessed using a visual analog scale (VAS) (0 represented no pain and 10 the worst pain ever experienced) at 15, 30, 60th minutes, and 2nd, 4th, 6th hours postoperatively.
Interventions
DRUGParacetamol
15 mg/kg IV (premixed with 0.9% sodium chloride to a total of 50 ml), preoperative single dose
DRUGDipyrone
15 mg/kg IV (premixed with 0.9% sodium chloride to a total of 50 ml), preoperative single dose
Sponsors
Baskent University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
8 Years to 15 Years
Healthy volunteers
Yes
Inclusion criteria
* American Society of Anesthesiologist (ASA) physical status I and II children undergoing elective lower abdominal surgery
Exclusion criteria
* increased intracranial pressure hemorrhagic diathesis infection at the puncture site Those with a known history of allergy to the study drugs
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change from pain intensity until postoperative 6 hours | Pain intensity recorded until postoperative 6 hours | The intensity of postoperative pain was assessed using a visual analog scale (VAS) (0 represented no pain and 10 the worst pain ever experienced) at 15, 30, 60th minutes, and 2nd, 4th, 6th hours postoperatively. |
Outcome results
None listed