Use of TpCO2 (Transcutaneous CO2 Measurement) as PaCO2 Predictor During NIV in Case of Acute Hypercapnic Respiratory Failure

Use of TpCO2 (Transcutaneous CO2 Measurement)as PaCO2 Predictor During Non Invasive Ventilation (NIV) in Case of Acute Hypercapnic Respiratory Failure

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01857635

Acronym

TpCO2-NIV

Enrollment

Registered

2013-05-20

Start date

2013-02-28

Completion date

2015-03-31

Last updated

2015-06-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypercapnic Respiratory Failure

Keywords

Acute respiratory failure, Hypercapnia, Non invasive ventilation, Transcutaneous CO2 measurement

Brief summary

In patients suffering from hypercapnic respiratory failure and treated by non invasive ventilation (NIV), the interest of using transcutaneous CO2 measurement to evaluate PaCO2 and PaCO2 variation over time is unknown and will be evaluated in this study. Measurements will be done during one-hour NIV treatments.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* ICU patient equipped with an arterial line * NIV treatment prescribed by the clinician in charge * Hypercapnia defined by PaCO2\> 42mmHg

Exclusion criteria

* Severe hemodynamic instability * Severe psychiatric disorders * Denied consent * Age \< 18 years

Design outcomes

Primary

Measure	Time frame
Comparison between TpCO2 (transcutaneous non invasive CO2 partial pressure measurement) and PaCO2 (obtained by blood gas analysis) values during NIV treatment.	sixty minutes

Countries

Switzerland

Outcome results