A Prospective Observational Cohort to Study the Genetics of Obstructive Sleep Apnea and Associated Co-Morbidities

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01857427

Enrollment

5000

Registered

2013-05-20

Start date

2012-08-01

Completion date

2026-12-01

Last updated

2026-03-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstructive Sleep Apnea

Brief summary

The primary objective of this study is to build a well characterized cohort of patients that will be used to determine the genetic variants associated with obstructive sleep apnea (OSA)and its co-morbidities.

Detailed description

The purpose of building the cohort is to allow the performance of genome-wide association studies with a large sample of patients that have been well-characterized using standardized procedures.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

We will recruit subjects who are: * 18 years of age and older. * Willing and able to give informed consent AND any of the following: * PSG (polysomnogram)requested by a physician based on clinical grounds * AHI (Apnea-hypopnea index) ≥ 5 episodes per hour based on a prior PSG.

Exclusion criteria

Incapable of giving informed consent * Under the age of 18

Design outcomes

Primary

Measure	Time frame	Description
Sleep Questionnaire	upon enrollment	Responses to sleep questionnaire

Countries

United States

Contacts

PRINCIPAL_INVESTIGATORUlysses Magalang, MD

Ohio State University

Outcome results