Eclampsia, Preeclampsia
Conditions
Keywords
preeclampsia, eclampsia, prediction, neutrophil-to Lymphocyte ratio
Brief summary
Neutrophil/lymphocyte ratio (NLR) is a marker of systemic inflammation and endothelial dysfunction. In recent years, it has been reported that the individual components of the differential white cell count, specifically the neutrophil and lymphocyte counts,may have clinical utility in predicting diseases. An elevated NLR has been shown to be a prognostic indicator in various malignancies. İn the literature, many studies have been shown that NLR have predictive value in determining the prognosis of various diseases (cardiac or noncardiac diseases ). However, little is known about the predictive values of NLR in pregnancy complications. This study aimed to evaluate the potential predictive value of NLR in preeclampsia- eclampsia.
Detailed description
In recent years, have been reported that the individual components of the differential white cell count, specifically the neutrophil and lymphocyte counts, may have clinical utility in predicting diseases. An elevated NLR has been shown to be a prognostic indicator in various malignancies. İn the literatüre have been shown that NLR have predictive value in determining the prognosis of various diseases (cardiac or noncardiac diseases.However, little is known about the predictive values of NLR and PLR in gestational DM, preeclampsia and the other pregnancy complications. Retrospective data were collected for patients who was diagnosed with , preeclampsia- eclampsia, The NLR was defined as the absolute neutrophil count divided by the absolute lymphocyte count.
Interventions
BIOLOGICALhigh neutrophil to lymphocyte ratio
OTHERnormal neutrophil-to Lymphocyte ratio
Sponsors
Zekai Tahir Burak Women's Health Research and Education Hospital
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
pregnant women who developing preeclampsia eclampsia at pregnancy
Exclusion criteria
Known chronically maternal disease multiple pregnancy older than 40 years old
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the effect of neutrophil lymphocyte ratio in preeclampsia eclampsia | up to 6 months | during 6 months ,the patients who was recorded with preeclampsi/eclampsia at our hospital ,first trimester whole blood count was taken and neutrophil lymphocyte ratio was calculated and recorded |
Countries
Turkey (Türkiye)
Outcome results
None listed