COPD
Conditions
Keywords
COPD, Physical activity
Brief summary
The purpose of this preliminary study is to examine the effects of a program that includes two-months of structured lab-based training. The proposed study will examine the effects of a lifestyle physical activity intervention designed to increase PA in people with moderate and severe COPD. The intervention includes a combination of (a) structured laboratory-based exercises with a behavioral intervention, (b) structured home-based exercises and (c) lifestyle physical activities performed at home. The subjects will be followed for a total of 18 weeks.
Detailed description
People with chronic obstructive pulmonary disease (COPD) experience a gradual decline in physical activity (PA). Exercise training in a structured pulmonary rehabilitation program can generate substantial gains in functional capacity, but increases in functional capacity do not necessarily lead to improvements in daily PA. The proposed study will examine the effects of a lifestyle physical activity intervention designed to increase PA in people with moderate and severe COPD. The intervention includes a combination of (a) structured laboratory-based exercises with a self-efficacy enhancing intervention, (b) structured home-based exercises and (c) lifestyle physical activities performed at home. The intervention gradually transitions subjects from the structured laboratory-based exercises that focus on walking and circuit training to fully integrated lifestyle physical activities that integrate structured home-based exercises and lifestyle physical activities into daily life. The purpose of this preliminary study is to examine the effects of a program that includes two-months of structured lab-based training and subjects will be followed for a total of 18 weeks.
Interventions
BEHAVIORALLifestyle physical activity - self-efficacy
Subjects will come into an exercise lab 2 days per week and perform 10-20 minutes of walking, 13 strength training exercises, stretching and a behavioral intervention including goal setting, etc.
Sponsors
University of Michigan
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
Lifestyle physical activity self-efficacy
Eligibility
Sex/Gender
ALL
Age
55 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* 55 years or older * Moderate to severe COPD (FEV1 \< 80% and \> 30% predicted; FEV1/FVC \<70%) as the primary health problem * Sedentary (less than 30 minutes of moderate activity 3 days/week)
Exclusion criteria
* No acute exacerbations or major illnesses requiring hospitalization in the last 8 weeks. * No history of other major lung diseases as primary pulmonary problem, history of a recent heart attack or recent onset of chest pains with activity or increasing episodes of chest pain (unstable angina). * No other health problems or mobility problems that limit physical activity. * No child bearing potential
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in physical activity measured by accelerometry | During initial visit (week 1), at 6 or 10 weeks (depending on group placement), and at week 18 | Subjects wear two activity monitors for seven consecutive days (Actipal and Actigraph). The study will compare the subject's activity level at the three time points listed. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in 6 minute walk test | During initial visit (week 1), at 6 or 10 weeks (depending on group placement), and at week 18 | Subjects complete a 6 minute walk test measuring the total distance he/she can walk in 6 minutes at the three time points listed. |
| Change in lower extremity function (Short Physical Performance Battery) | During initial visit (week 1), at 6 or 10 weeks (depending on group placement), and at week 18 | Subjects complete a performance test measuring balance, gait speed, and leg strength (using a chair stand test) at the three time points listed. |
| Change in dyspnea and fatigue (Pulmonary Functional Status and Dyspnea Questionnaire-Modified) | During initial visit (week 1), at 6 or 10 weeks (depending on group placement), and at week 18 | Subjects complete a questionnaire answering questions about their level of dyspnea in various daily activities at the three time points listed. |
| Change in physical activity measured by CHAMPS questionnaire | During initial visit (week 1), at 6 or 10 weeks (depending on group placement), and at week 18 | Subjects fill out a questionnaire of their perceived physical activity at the three time points listed. |
Countries
United States
Outcome results
None listed