Repetitive Transcranial Magnetic Stimulation in Patients With Hemiplegic Stroke

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01855633

Enrollment

Registered

2013-05-16

Start date

2013-04-26

Completion date

2040-12-01

Last updated

2026-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Brief summary

Stroke is one of the major causes of death in the World. Many stroke survivors may suffer from long-term sequelae of stroke such as hemiplegia. The effects of rehabilitation therapy are limited. The development of new treatment strategies is essential. Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive method to stimulate the focal area of the brain for restoring brain function. The aim of this study is to investigate the therapeutic effect of rTMS on the motor recovery in patients with hemiplegic stroke.

Interventions

DEVICETraditional Theta burst stimulation (TBS)

DEVICEModified TBS rTMS

DEVICESham rTMS

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* stroke patients with motor weakness * Medical research council (MRC) grade 0-4 * More than 2 weeks after stroke onset * Age 18 years and older * Able to provide consent for the protocol

Exclusion criteria

* History of previous symptomatic stroke * pregnant women * Persons with surgically or traumatically implanted foreign bodies such as a pacemaker, an implanted medication pump, a metal plate in the skull, or metal inside the skull or eyes (other than dental appliances or fillings), intracardiac lines that may pose a physical hazard during magnetic stimulation will also be excluded * Patients with history of seizure disorder or epilepsy * Subjects without the capacity to give informed consent

Design outcomes

Primary

Measure	Time frame	Description
Keyboard tapping test	1 day	Participants will be asked to tap a key of a computer keyboard as fast as possible in five seconds. They will be asked to do three times. We will measure the number of tapping. The primary outcome will be the averaged data of the numbers.This will be done before and after 5-day rTMS intervention.

Countries

South Korea

Contacts

CONTACTSuk Yun Kang, MD, PhD

sukyunkang@hanmail.net82-31-8086-2310

CONTACTAh-Young Jun, MD, MS

ayjun@hallym.or.kr82-31-8086-2310

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 28, 2026