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Low Tube Voltage Computed Tomographic (CT) Urography Using Low Concentration Iodine Contrast Agent

Low Tube Voltage Computed Tomographic (CT) Urography Using Low Concentration Iodine Contrast Agent: a Comparison Study With Conventional CT Urography

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01855204
Enrollment
64
Registered
2013-05-16
Start date
2013-04-30
Completion date
2014-04-30
Last updated
2013-12-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exposure to Medical Diagnostic Radiation

Keywords

Computed Tomography, Spiral, Urography, Radiation dosage, Contrast media

Brief summary

Computed Tomographic (CT) urography is the best imaging modality to evaluate obstructing lesions of urinary tract such as urinary stone, tumor and inflammatory lesion. The purpose of our study is to compare images of CT urography performed by low voltage and low concentrated iodine CT contrast with them of conventional CT urography.

Detailed description

Computed Tomographic (CT) urography is the best imaging modality to evaluate obstructing lesions of urinary tract such as urinary stone, tumor and inflammatory lesion. It is needed that CT urography should have the high contrast between target lesion described as filling defect and adjacent contrast filled urinary tract. For the implementation of high contras, conventional CT urography has been performed with higher voltage and higher concentrated CT contrast than another CT protocols. The higher voltage results in the more radiation exposure. And the intravenous injection of higher concentrated CT contrast results in the increase of the prevalence of contrast induced nephrotoxicity. The purpose of our study is to compare images of CT urography performed by low voltage and low concentrated iodine CT contrast with them of conventional CT urography.

Interventions

RADIATIONComputed tomographic urography

Computed tomographic (CT) urography was done with the protocols of low voltage and low iodine concentration.

Sponsors

Seoul National University Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
20 Years to 70 Years
Healthy volunteers
Yes

Inclusion criteria

* Patients to perform Computed Tomographic (CT) urography * Patients without diminish of renal function (serum creatinine: more than 1.4 mg/dl & glomerular filtration rate: more than 34 mL/min/1.73 m2)

Exclusion criteria

* patients to have operations and/or injuries of urinary system * patients to have the histories of anaphylaxis or allergic reaction about intravenous iodine contrast material

Design outcomes

Primary

MeasureTime frame
Measurement of Radiation DoseThe day of admission (within 24hours)

Countries

South Korea

Contacts

Primary ContactJeong Yeon Cho, Professor
radjycho@snu.ac.kr82-2-2072-3074
Backup ContactSang Youn Kim, Professor
iwishluv@empas.com82-2-2072-3321

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026