Chronic Heart Failure
Conditions
Keywords
chronic heart failure, drug-drug interactions, pharmacist's intervention
Brief summary
Drug-drug interactions (DDIs) are common in patients with chronic heart failure (CHF) and their incidence increases with the number of drugs that the patients are prescribed for treatment of their condition. Data bases often detect DDIs that are of high clinical relevance. The investigators have performed this study in order to detect clinically significant DDIs and to diminish their occurrence by sending notification about DDIs to attending physician.
Interventions
BEHAVIORALAdvice on DDIs
Sponsors
The University Clinic of Pulmonary and Allergic Diseases Golnik
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Patients admitted with diagnosis of CHF I50.0 - I50.9 and I11.0 - I11.9 (ICD-10) * patients treated with at least two drugs
Exclusion criteria
* Patients admitted to other conditions
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| To assess the difference in frequency and severity of clinically significant DDIs in control arm and interventional arm between admission and discharge | 90 days | We will measure the difference in clinically significant DDIs between admission and discharge. The doctors in control group will not receive the advice about DDIs between drugs prescribed to patient, while the doctors in interventional group will. With this will will assess the impact of the advice in the occurence of DDIs between admission and discharge for both groups. |
Countries
Slovenia
Contacts
Primary ContactMitja Lainscak, PhD
Outcome results
None listed