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The Influence of Pneumoperitoneum on Minimal Invasive Cardiac Output Measurements

The Influence of Pneumoperitoneum on Minimal Invasive Cardiac Output Measurements

Status
Terminated
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01854307
Enrollment
5
Registered
2013-05-15
Start date
2013-05-31
Completion date
Unknown
Last updated
2016-01-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pneumoperitoneum

Keywords

Difference of, measurements, before and after

Brief summary

Perioperative goal directed fluid therapy may reduce complication rate after surgery. Minimal invasive cardiac output monitoring is a key method to guide fluid therapy. More operations are being performed by keyhole surgery (laparoscopy). For laparoscopy, the abdomen is filled with carbon dioxide. Increased pressure in the abdomen may influence minimal cardiac output monitoring, therefore minimal cardiac output monitoring is not recommended during laparoscopy. This study aims to validate minimal cardiac output monitoring during laparoscopy and therefore facilitate for goal directed fluid therapy.

Interventions

PROCEDUREPneumoperitoneum and SVV/PPV

Sponsors

Haukeland University Hospital
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Eligibility

Sex/Gender
MALE
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* all patients \>18 years scheduled for robot-assisted prostatectomy * able to give informed consent

Exclusion criteria

* Patient with atrial fibrillation or other non-regular rhythm. * Severe aorta/mitral stenosis * Not able to give informed consent

Design outcomes

Primary

MeasureTime frameDescription
Change of stroke volume variation and pulse pressure variation during pneumoperitoneumperoperativeChange in PPV/SVV(LiDCO), PPV(Philips) and SVV/CO(TEE) in percent before and after pneumoperitoneum.

Secondary

MeasureTime frame
Difference in measurements from different methods of minimal cardiac output monitoring.peroperative
Effect of fluid bolus under pneumoperitoneum (responder vs. non-responder)peroperative

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026