Parkinsonian Disorders
Conditions
Brief summary
Freezing of gait (FOG) means that patients cannot walk without any known causes, other than parkinsonism, which is very disabling symptom. Patients descirbe their feeling of the feet suddenly being glued to the floor. Transcranial magnetic stiumation is a noninvasive procedure using electromagnetic induction to stimulate brain. Transcranial magnetic stiumation (rTMS) can selectively change brain activity to enhance desired effects. The aim of this study is to the therapeutic effect of rTMS for the FOG.
Interventions
DEVICErTMS Motor cortex
DEVICErTMS Supplementary motor area
Sponsors
Dongtan Sacred Heart Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* Parkinson's disease or Primary progressive freezing of gait * age 18 and older * Freezing of gait
Exclusion criteria
* pregnant or any, other medical, surgical, neurological or psychiatric conditions * other restrictions which prevent you from undergoing TMS recording, such as; surgically or traumatically implanted foreign bodies such as a pacemaker, an implanted medication pump, a metal plate in the skull, or metal inside the skull or eyes (other than dental appliances or fillings), and/ or heart/cardiac lines * any past or current history of seizure disorder or epilepsy * unable to give informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The number of steps | 2 days | The number of steps during the stand-walk-sit (SWS) test |
Secondary
| Measure | Time frame |
|---|---|
| The completion time during the SWS test | 2 days |
| Freezing episodes of gait trajectory | 2 days |
| Patient and Clinical Global Impression Scale | 2 days |
Countries
South Korea
Outcome results
None listed