Androgenic Alopecia
Conditions
Keywords
Pumpkin seed oil, Hair growth, Men
Brief summary
Androgenic alopecia is the most common cause of hair loss in men. Finasteride and minoxidil are available in treatment of androgenetic alopecia, although the former causes decreased libido or ejaculate volume, erectile dysfunction, the latter causes scaling, itching of the scalp. Recently, Pulpkin Seed Oil shows some improved clinical efficacy on scalp hair growth in men with androgenetic alopecia, but there is no evidence to support this. The investigators conducted a randomized, double-blind, placebo-controlled efficacy and tolerability trial of Pumpkin seed oil (400mg/day)therapy in male patients with androgenetic alopecia.
Interventions
DIETARY_SUPPLEMENT400mg /day during 6 months
Sponsors
Dream Plus
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
MALE
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* 18 to 65 years of age * Androgenetic alopecia of Norwood-Hamilton scale grade II-V
Exclusion criteria
* Severe medical problems including renal problems, prostate diseases, diabetes mellitus o * Patients who took any medicine which can affect the hair growth in recent 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| investigator assessment score using photographs of scalp hair | at weeks 12 and 24 |
Secondary
| Measure | Time frame |
|---|---|
| patient self-assessment scores | at weeks 12 and 24 |
Other
| Measure | Time frame |
|---|---|
| hair analysis using phototrichogram | at weeks 12 and 24 |
Countries
South Korea
Outcome results
None listed