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ADAPT A Direct Aspiration, First Pass Technique for the Endovascular Treatment of Stroke

ADAPT A Direct Aspiration, First Pass Technique for the Endovascular Treatment of Stroke

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01852227
Enrollment
500
Registered
2013-05-13
Start date
2013-06-30
Completion date
2016-05-31
Last updated
2017-10-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke Technique

Brief summary

In collaboration with the Neurointerventional programs at state university of new york Buffalo, state university of new york Stonybrook, Swedish Medical Center, Erlanger Health System, Vanderbilt University, and West Virginia University School of Medicine, the investigators aim to prospectively collect experiences where direct aspiration as a first pass technique is used for thrombectomy procedures. The investigators also want to compare specific characteristics from these cases to other stroke cases where traditional thrombectomy devices were used.

Detailed description

Traditionally, at a physician's discretion, first pass attempts at thrombectomy procedures are performed with any number of FDA cleared catheters, guide wires, and devices designed for efficient removal of clot within an intracranial vessel. Among institutions involved in this case study, the latest devices are readily available and fully support standard treatment paradigms. However, several cases, recently completed, using only large bore catheter and aspiration have anecdotally demonstrated a superior ability to remove clot from vessels, restoring blood flow to the affected vessel and brain tissue. In these limited number of cases, full restoration of blood flow has been achieved. While this combination of approved devices is minimalistic, the efficiency of the procedure, rapid technical success, and relative simplicity of the approach is unique and should be thoroughly reviewed and possibly prepared for publication.

Interventions

None listed

Sponsors

State University of New York - Downstate Medical Center
CollaboratorOTHER
Stony Brook University
CollaboratorOTHER
Swedish Medical Center
CollaboratorOTHER
Vanderbilt University
CollaboratorOTHER
West Virginia University
CollaboratorOTHER
Medical University of South Carolina
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* All patients who were treated with direct aspiration as a first pass choice or treated with a stent retriever will be included.

Exclusion criteria

* Patients not treated with either direct aspiration as a first pass, or stent retriever will not be included.

Design outcomes

Primary

MeasureTime frameDescription
Discharge national institutes of health stroke scale (NIHSS)approximately 7 days after index strokea national institutes of health stroke scale (NIHSS) will be obtained at the time of the each patient's discharge or approximately 7 days

Secondary

MeasureTime frameDescription
90 day modified Rankin Score (mRS)90 days after procedure90 days after procedure each patient's modified Rankin Score will be obtained.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026