Nasal Obstruction
Conditions
Keywords
Nasal obstruction, Vibrissae, Nasal hair
Brief summary
Nasal obstruction is a common complaint prompting presentation to an otolaryngologist. Many studies have been performed quantifying and describing the impact of a number of factors on symptoms of nasal obstruction, including anatomical, neoplastic, infectious, and inflammatory causes. Despite this scrutiny, no attention has been paid to the nasal vibrissae as a potential anatomical contributor to nasal obstruction. The proposed study intends to elucidate that contribution, if any exists.
Interventions
PROCEDUREVibrissae trimming
Patients will have oxymetazoline administered prior to assessment of outcome measures to ensure minimal impact of erectile mucosal tissue on measurement.
DRUGApplication of oxymetazoline
Afrin will be administered to minimize the impact of erectile mucosal tissue on obstruction.
Sponsors
Mayo Clinic
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Presence of nasal vibrissae * Able to tolerate rhinomanometry
Exclusion criteria
* Anatomical or other obvious cause of obstruction * Claustrophobia with rhinomanometry mask
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Nasal airflow/pressure | Participants will undergo assessment over a 30 minute period, no follow-up | Objective measures include airflow and pressure as assessed by Rhinomanometry. |
| Subjective Nasal Obstruction | Participants will undergo assessment over a 30 minute period, no follow-up | Subjective measures will be assessed via the modified version of the NOSE outcome instrument-a validated test of subjective nasal obstruction |
Countries
United States
Outcome results
None listed