Intracranial Hypertension
Conditions
Keywords
Intracranial hypertension, intracranial elastance
Brief summary
The aim of this study is to determine whether we can predict the intracranial pressure using near infra-red spectroscopy
Detailed description
The management of intracranial hypertension requires the presence of an intracranial pressure monitor. We are investigating whether the waveforms obtained from a near infrared spectroscopy device can predict what the intracranial pressure is non-invasively. * Patients with intracranial hypertension who are intubated and ventilated in the ICU will be recruited * we will record there intracranial pressure and systemic arterial pressure * recordings from the near infrared device will be recorded and analysed off-line * we will correlate the waveform tracings from near infrared spectroscopy and the arterial tracing
Interventions
None listed
Sponsors
University of Virginia
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
Patients with an intracranial pressure monitor and arterial catheter who are admitted to the ICU
Exclusion criteria
Less than 18 years
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Intracranial elastance | Participants will be followed while an arterial line and intracranial pressure monitor is present duing the ICU admission. This is expected to be an average of 5 days. | Intracranial elastance (δP/δV)will be measured by dividing the pulse pressure of an invasive arterial blood pressure by the amplitude of high frequency oscillations in the near infrared (NIR) absorbance waveforms. |
Countries
United States
Outcome results
None listed