Latent Tuberculosis, Tuberculosis
Conditions
Brief summary
TST will be analyzed in young general population in Korea. Young adults undertake TST as CDC recommendation. Participants with chest radiograph showing active TB lesion are excluded from this study.
Detailed description
Enroll criteria * A term of whole military conscripts per year in one Reserve Force Battalion * Military conscripts gather from all around area in Korea randomly * Each participant undertake a chest X-ray (CXR) and blood tests including human immunodeficiency virus (HIV) at the start of initiatory training. Exclusion Criteria * Chest X-ray suggesting active TB * HIV positive in serology Design * After giving informed consent, all participants receive one-step TST following standard procedures. * The largest transverse diameter of induration is measured 48-72hr after injection. * The investigator and these trained nurses were blinded to the status of their demographic characteristics.
Interventions
None listed
Sponsors
Asan Medical Center
Study design
Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
MALE
Age
18 Years to 29 Years
Healthy volunteers
Yes
Inclusion criteria
* Military Conscripts age 18-29 years old
Exclusion criteria
* Chest X-ray suggests active TB * Positive HIV in serology
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| TST positivity TST rate | Two days after tuberculin injection | Investigators measure induration size of tuberculin skin test 48 after tuberculin injection. |
Secondary
| Measure | Time frame |
|---|---|
| BCG scar rates | The day of tuberculin injection |
Countries
South Korea
Outcome results
None listed