Lactating Women Who Give Their Milk to One of the 6 Milk Banks Participating in the Study
Conditions
Keywords
Public Health, Epidemiology, Pharmacy Toxicology, Perinatal period
Brief summary
Recent international data have shown that the levels of chemical substances found in human milk could be at risk for breastfed infants. New data are necessary to assess this risk among French newborns.
Detailed description
The objective of this study is to assess levels of certain contaminants in breastmilk. Measurements will be made on breastmilk samples collected in Milk Bank but not suitable for infants due to bacteriological reasons. 6 Milk Banks well distributed on the French territory will be contacted to participate. 180 women will be included. Women who gave their milk and correspond to the inclusion criteria (in particular breastfeeding a child under 6 months at the time of the donation) will be contacted by the investigator by phone. They will be asked to fill in a written consent as well as a questionnaire on socio-demographic data, pregnancy related information and potential environmental exposures. 2 breastmilk samples of 50 mL will be sendsending to the lab for analysis and 2 samples of 50 mL will be collected.
Interventions
OTHERBreastmilk
to measure levels of contaminants in human breastmilk samples
Sponsors
Assistance Publique - Hôpitaux de Paris
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
For the samples: * Not allowed to use for bacteriological reasons * Breastmilk samples from lactating women between delivery and 6 months (+/- 1 month) of the infant For the mothers: * Age \> or = 18 years * Lived on the French territory * Well french writer and speaker * Mother child couple in good health * Non opposability
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Presence of contaminants (PCB, dioxins, furans and brominated flame retardants) | at the moment of the milk's donation | analysis of contaminants |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| evaluate the concentration of other contaminants, perfluorinated compounds, organochlorine pesticides and inorganic compounds | at the moment of the milk's donation | analysis of contaminants |
| To estimate the exposure of breastfed infants and to assess the risk in this population | at the moment of the milk's donation | statistical analysis |
Countries
France
Outcome results
None listed